PIPFRIL-TZ-4500
Piperacillin 4000mg + Tazobactam 500mg Injection
Extended-spectrum antipseudomonal beta-lactam with tazobactam — first-line empirical therapy in severe nosocomial infections.

Product Specifications
| Brand Name | PIPFRIL-TZ-4500 |
|---|---|
| Generic / Composition | Piperacillin Sodium IP equivalent to Piperacillin 4000mg + Tazobactam Sodium IP equivalent to Tazobactam 500mg |
| Therapeutic Category | Extended-Spectrum Penicillin + Beta-lactamase Inhibitor |
| Dosage Form | Lyophilized powder for injection |
| Strength | 4.5g (4000mg + 500mg) |
| Route of Administration | Intravenous infusion |
| Pack Size | 1 Vial with WFI |
| Storage | Store below 25°C. Protect from light. |
| Manufacturer | Biofril Healthcare Pvt. Ltd. · WHO-GMP Plant, Nalagarh HP |
| Prescription Status | Rx — To be sold by retail on the prescription of a Registered Medical Practitioner |
Indications & Clinical Applications
PIPFRIL-TZ-4500 is indicated for moderate to severe infections caused by susceptible bacteria, including ESBL producers and Pseudomonas.
- Nosocomial pneumonia including ventilator-associated
- Complicated intra-abdominal infections
- Complicated skin and soft tissue infections
- Febrile neutropenia (empiric therapy)
- Septicaemia in hospitalized patients
- Complicated UTI
Product Features
- Anti-pseudomonal coverage
- Tazobactam restores activity against ESBL producers
- Hospital ICU first-line empirical option
- COA with every batch
- WHO-GMP manufactured
Warnings & Precautions
Contraindicated in penicillin allergy. Adjust dose in renal impairment. Monitor for bleeding (high sodium load), C. difficile diarrhoea, and electrolyte disturbances.
This information is intended for healthcare professionals only. Always consult the complete product insert and a registered medical practitioner before prescribing or using. Biofril Healthcare is committed to pharmacovigilance — please report any adverse events to biofrilhealthcare@gmail.com.
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